Publikationen Labor Stammzellforschung

• Originalarbeiten

Kraetzel K, Stoelcker B, Eißner G, Multhoff G, Pfeifer M, Holler E, Schulz C: NKG2D-dependent effector function of bronchial epithelium activated alloreative T cells.
Eur Respir J 32:563-570, 2008

Holler E, Rogler G, Brenmoehl J, Hahn J, Greinix H, Dickinson AM, Socie G, Wolff D, Finke J, Fischer G, Jackson G, Rocha V, Hilgendorf I, Eißner G, Marienhagen J, Andreesen R:
The role of genetic variants of NOD2/CARD15, a receptor of the innate immune system, in GvHD and complications following related and unrelated donor hematopoeitic stem cell transplantation. Int J Imunogenet 35:381-384, 2008

Gerbitz A, Hillemanns P, Schmid C, Wilke A, Jayaraman R, Kolb HJ, Eißner G, Holler E:
Influence of polymorphism within the heme oxygenase-I promoter on overall survival and transplantation-related mortality after allogeneic stem cell transplantation.  Biol Blood Marrow Transplant 14:1180-1189, 2008

Gottfried E, Kreutz M, Haffner S, Holler E, Iacobelli M, Andreesen R, Eißner G:
Differentiation of human tumor-associated dendritic cells into endothelial-like cells: an alternative pathway of tumor angiogenesis. Scand J Immunol 65:329-335, 2007 (Viking Prize 2007 of the Scandinavian Society of Immunology)

Hennig R, Kehl T, Noor S, Ding XZ, Rao SM, Bergmann F, Fürstenberger G, Büchler MW, Freiss H, Krieg P, Adrian TE:  15-lipoxygenase-1production is lost in pancreatic cancer and overexpression of the gene inhibits tumor cell growth.  Neoplasia 9:917-926, 2007

Rothhammer T, Bataille F, Spruss T, Eißner G, Bosserhoff AK:
Functional implication of BMP-4 expression on angiogenesis in malignant melanoma.
Oncogene 26:4158-4170, 2007

Koehl GE, Geissler EK, Iacobelli M, Frei C, Burger V, Haffner S, Holler E, Andreesen R, Schlitt HJ, Eißner G: Defibrotide, an endothelium protecting and stabilizing drug, has anti-angiogenic potential in vitro and in vivo. Cancer Biology and Therapy 6:686-690, 2007

• In Zeitschriften publizierte Kongressbeiträge

Echart C, Eißner G, Holler E, Iacobelli M: Defibrotide protects human microvascular endothelial cells from fludarabine-mediated pro-inflammatory and pro-apoptotic signals: a microarray (Affimetrix) analysis. Bone Marrow Transplant 45 (Suppl. 1):S281, 2010

Eißner G, Holler E, Kesikli A, Haffner S, Hartmann I, Reichart B: CD4+CD25+FoxP3+ regulatory T cells (Treg) unusually enhance allogeneic lysis of human microvascular endothelial cells by CD8+ cytotoxic T lymphocytes. Eur J Immunol 39 (Suppl. 1):S613, 2009

Eißner G, Koehl GE, Geissler EK, Holler E, Iacobelli M:
Defibrotide, an anti-thrombotic drug, prevents angiogenesis in vitro and in vivo. Thromb Res 120 (Suppl. 2), S147, 2007

• Kongressbeiträge

Eißner G, Kesikli A, Hartmann I; Holler E, Haffner S, Reichart B: CD4+CD25+FoxP3+ regulatory T cells enhance the cytotoxic activity of endothelial-specific CD8+/CD28- cytotoxic T lymphocytes. Regulatory Networks in Immunity and Inflammation (Abcam),  Napa Valley, 08.06.-10.06.2010 (Poster)

Eißner, G; Hartmann, I; Haffner, S; Meiser, B; Reichart, B: Regulatory T cells enhance allogeneic lysis of human endothelial cells by T lymphocytes. Thorac cardiovasc Surg 2010; 58: MP47-. 39th Annual Meeting of the German Society for Thoracic and Cardiovascular Surgery, 14.-17.02. 2010

Eißner G, Hollweck G, Hartmann I, Noor S, Meiser B, Reichart B: Mesenchymal stem cells from umbilical cord tissue differentiate into cardiomyocytes and constitute an alternative candidate for cardiac tissue engineering. Stem Cells 2009 (Abcam), Antigua, 19.-22.11.2009 (Poster)

Noor S, Hollweck T, Haffner S, Holler E, Iacobelli M, Reichart B, Eißner G: Defibrotide, an anti-atheroslerotic and anti-apoptotic drug, prevents leukotriene B4 (LTB4) expression and caspase 3 activation in human microvascular endothelial cells. 38. Jahrestagung der Deutschen Gesellschaft für Thorax-, Herz- und Gefäßchirurgie, 15.-18.02.2009 (Poster)

Echart C, Iacobelli M, Ignoni T, Ferro L, Eißner G: Effect of Defibrotide on the endothelium and on the tumor microenvironment. 13th International Congress of Immunology, Rio de Janeiro, Brasilien, 21.-25.08.2007 (Poster)

Echart C, Iacobelli M, Ignoni T, Ferro L, Eißner G: Defibrotide protects endothelial cells from stress-induced cell death via inhibition of the extrinsic apoptosis pathway. XXI^st Congress of the International Society of Thrombosis and Hemostasis, Genf, Schweiz, 06.-12.07.2007 (Poster)

Eißner G, Koehl GE, Echart C, Geissler EK, Iacobelli M: Defibrotide, an endothelium stabiliziung drug, prevents angiogenesis in vitro and in vivo. Los Angeles CA, USA, 14.-18.04.2007 (Poster)

Eißner G, Koehl GE, Geissler EG, Andreesen R, Holler E, Iaobelli M: Defibrotide, a DNA-based drug, modulates immune functions of the endothelium – impact for cancer therapy and transplantation. Keystone Symposium: „Mechanisms Linking Inflammation and Cancer“, Santa, New Mexico, USA, 10.-15.02.2007 (Poster)